Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dusp12Dual specificity phosphatase 12. (299 aa)    
Predicted Functional Partners:
xylb
Xylulokinase homolog (H. influenzae).
    
   0.818
ENSACLP00000016377
Eukaryotic translation initiation factor 5.
   
   0.803
agl
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b.
    
   0.764
ccnh
Cyclin H; Belongs to the cyclin family.
    
   0.754
LOC113008023
BRCA1 associated RING domain 1.
   
 0.741
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; Belongs to the DEAD box helicase family.
   
 
 0.687
LOC113017928
Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.658
hsd17b12
Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.658
lin28b
Lin-28 homolog B (C. elegans).
    
 
 0.656
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1.
      
 0.655
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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