STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC113027040L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)    
Predicted Functional Partners:
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.977
got2
Aspartate aminotransferase.
   
 0.956
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.954
LOC113030206
Malate synthase-like.
  
 0.947
ENSACLP00000010419
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.945
LOC113025482
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.945
LOC113031950
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.945
pc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.945
LOC113025863
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.943
LOC113024994
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.943
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.