Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACLP00000001939Methyltransferase like 4; Belongs to the MT-A70-like family. (409 aa)    
Predicted Functional Partners:
mettl14
Methyltransferase like 14; Belongs to the MT-A70-like family.
      
 0.897
mettl3
Methyltransferase like 3; Belongs to the MT-A70-like family.
      
 0.892
ENSACLP00000036438
N-6 adenine-specific DNA methyltransferase 1.
      
 0.866
ENSACLP00000002055
Structural maintenance of chromosomes flexible hinge domain containing 1.
   
  
 0.863
alkbh4
AlkB homolog 4, lysine demthylase.
      
 0.786
ENSACLP00000030418
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]
      
 0.715
ENSACLP00000026406
AlkB homolog 1, histone H2A dioxygenase.
      
 0.705
wtap
WT1 associated protein.
      
 0.698
alkbh5
AlkB homolog 5, RNA demethylase.
      
 0.679
alkbh2
AlkB homolog 2, alpha-ketoglutarate-dependent dioxygenase.
      
 0.669
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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