Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113014010IlGF domain-containing protein. (185 aa)    
Predicted Functional Partners:
LOC113026105
Tyrosine-protein kinase receptor.
    
 0.915
igf1r
Tyrosine-protein kinase receptor.
    
 0.915
LOC113011234
Tyrosine-protein kinase receptor.
    
 0.895
LOC113015984
Tyrosine-protein kinase receptor.
    
 0.895
LOC113029192
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.891
igf2
Insulin-like growth factor 2b.
     
 0.891
ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.891
met
MET proto-oncogene, receptor tyrosine kinase.
    
  0.885
ENSACLP00000014054
Tyrosine-protein kinase receptor.
    
  0.881
LOC113022294
Eph receptor A2 a.
    
  0.881
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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