Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rfc4Replication factor C (activator 1) 4. (357 aa)    
Predicted Functional Partners:
rfc3
Replication factor C (activator 1) 3.
   
0.999
rfc2
Replication factor C (activator 1) 2.
  
0.999
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.999
rfc1
Replication factor C subunit 1.
   
 0.999
rfc5
Replication factor C (activator 1) 5.
  
0.999
chtf18
AAA domain-containing protein.
   
 0.997
dscc1
DNA replication and sister chromatid cohesion 1.
   
 0.997
chtf8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae).
   
 0.996
rad17
RAD17 checkpoint clamp loader component.
    
 0.994
ENSACLP00000001994
ATPase family AAA domain containing 5a.
   
 0.992
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (20%) [HD]