Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113033525Solute carrier family 2 member 11b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (511 aa)    
Predicted Functional Partners:
LOC113030206
Malate synthase-like.
  
 0.801
LOC113018712
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.695
mitf
Melanocyte inducing transcription factor a.
   
 
 0.691
kirrel2
Kirre like nephrin family adhesion molecule 3, like.
      
 0.668
tspan10
Tetraspanin.
      
 0.668
LOC113008772
Pleiotrophin.
      
 0.667
LOC113024712
Solute carrier family 22 member 7a.
  
 
 0.661
LOC113030523
Si:ch211-114c12.2.
     
 0.660
LOC113022617
Premelanosome protein a.
      
 0.655
dct
Dopachrome tautomerase.
   
 
 0.643
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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