Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DNM1LDynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (731 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
   
 0.959
LOC113024462
Mitochondrial elongation factor 2.
    
 
 0.935
MFF
Miff domain-containing protein.
    
 
 0.931
pgam5
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.
    
 0.929
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.913
marchf5
Membrane-associated ring finger (C3HC4) 5.
    
 0.898
ENSACLP00000029358
RING-CH-type domain-containing protein.
    
 0.898
LOC113019113
Receptor-interacting serine-threonine kinase 3.
    
 0.887
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.886
ENSACLP00000037208
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.886
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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