Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sort1Sortilin. (832 aa)    
Predicted Functional Partners:
ENSACLP00000037698
Nerve growth factor receptor a (TNFR superfamily, member 16).
    
 0.993
ENSACLP00000031169
Neurotensin.
    
 
 0.957
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
    
 
 0.948
LOC113012951
Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.
    
 
 0.943
LOC113019366
Nerve growth factor receptor b.
    
  0.875
LOC113022678
Proteasome endopeptidase complex; Belongs to the peptidase T1A family.
     
  0.872
LOC113009079
Sortilin.
     
  0.872
LOC113023714
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.860
LOC113021179
Uncharacterized protein.
    
 
 0.860
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.854
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.