Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pgap1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (938 aa)    
Predicted Functional Partners:
mppe1
Metallophosphoesterase 1.
    
 0.966
ENSACLP00000015262
Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.
    
 0.959
pigk
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.956
ENSACLP00000036502
Phosphatidylinositol glycan anchor biosynthesis, class T.
     
 0.953
gpaa1
Glycosylphosphatidylinositol anchor attachment 1.
     
 0.948
pigs
Phosphatidylinositol glycan anchor biosynthesis, class S.
    
 0.941
LOC113021887
Phosphatidylinositol glycan anchor biosynthesis, class U.
     
 0.908
PIGU
Phosphatidylinositol glycan anchor biosynthesis class U.
     
 0.908
tmed10
Transmembrane p24 trafficking protein 10.
    
 
 0.906
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
   
 
 0.894
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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