Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZFYVE1Zinc finger FYVE-type containing 1. (786 aa)    
Predicted Functional Partners:
vps28
Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
    
 0.900
stam
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1.
   
 0.885
stam2
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2.
   
 0.885
LOC113007161
Zinc finger, FYVE domain containing 1.
     
  0.872
LOC113036442
Si:ch211-11n16.2.
     
  0.872
RPS27A
Ribosomal protein S27a.
    
  0.856
ENSACLP00000003123
UEV and lactate/malate dehyrogenase domains.
    
 0.851
LOC113027041
Zgc:123278.
    
 0.838
tsg101
Tumor susceptibility 101a.
    
 0.838
ptpn23
Protein tyrosine phosphatase, non-receptor type 23, a.
   
 0.829
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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