Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fgfbp3Fibroblast growth factor binding protein 3. (237 aa)    
Predicted Functional Partners:
LOC113016435
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.683
hdhd3
Haloacid dehalogenase-like hydrolase domain containing 3.
      
 0.670
uchl5
Ubiquitin carboxyl-terminal hydrolase.
      
 0.654
fgf10
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.634
btbd9
BTB (POZ) domain containing 9.
      
 0.628
LOC113025830
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.618
fgf3
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
  0.605
LOC113035561
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
     
  0.582
fgf1
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
     
  0.582
znf592
Uncharacterized protein.
      
 0.546
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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