Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1L1Uncharacterized protein. (1743 aa)    
Predicted Functional Partners:
ENSACLP00000001671
Afadin, adherens junction formation factor a.
    
 0.813
ENSACLP00000003584
Uncharacterized protein.
    
 0.813
LOC113008802
Uncharacterized protein.
    
 0.812
LOC113021951
Uncharacterized protein.
    
 0.812
RAP2A
RAP2A, member of RAS oncogene family.
    
 0.647
LOC113007449
RAP2C, member of RAS oncogene family.
    
 0.647
ENSACLP00000019843
Ral GTPase activating protein, beta subunit (non-catalytic).
   
 0.605
LOC113024725
Rap-GAP domain-containing protein.
   
 0.605
ENSACLP00000020287
Leucine zipper, putative tumor suppressor family member 3b.
    
 
 0.602
LOC113028147
Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family.
    
 
 0.602
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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