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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (627 aa)    
Predicted Functional Partners:
lig3
DNA ligase.
   
 0.999
polb
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
   
 0.986
lig1
DNA ligase.
   
 0.971
pnkp
Polynucleotide kinase 3'-phosphatase.
   
 0.971
lig4
DNA ligase.
   
 0.970
rec114
REC114 meiotic recombination protein.
   
 0.960
ENSACLP00000027601
Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family.
   
 0.951
ENSACLP00000027693
Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family.
   
 0.951
ENSACLP00000003992
Uncharacterized protein.
    
 
 0.936
ENSACLP00000022919
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.934
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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