STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000002301BMP2 inducible kinase. (487 aa)    
Predicted Functional Partners:
ENSACLP00000009309
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.873
reps2
RALBP1 associated Eps domain containing 2.
    
 0.865
reps1
RALBP1 associated Eps domain containing 1.
    
 0.865
ENSACLP00000002940
DnaJ (Hsp40) homolog, subfamily C, member 6.
 
 
 0.835
gak
Cyclin G associated kinase.
   
0.835
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.830
ENSACLP00000015691
Epidermal growth factor receptor pathway substrate 15 like 1.
    
 0.824
eps15l1
Epidermal growth factor receptor pathway substrate 15-like 1a.
    
 0.824
ENSACLP00000034552
Epidermal growth factor receptor pathway substrate 15.
    
 0.824
LOC113030513
AP complex subunit beta.
    
 0.784
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.