Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000002322Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (998 aa)    
Predicted Functional Partners:
ENSACLP00000030532
Kit ligand a.
   
 0.987
il34
Interleukin 34.
   
 0.987
LOC113013742
Uncharacterized protein.
   
 0.987
grb2
Growth factor receptor-bound protein 2b.
   
 0.976
spi1
Spi-1 proto-oncogene b.
   
 0.942
ENSACLP00000013150
Colony stimulating factor 1 receptor, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
  
  
 
0.938
ENSACLP00000029955
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
    
 0.923
vegfa
Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.
    
 0.916
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
     
 0.912
ENSACLP00000034296
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.907
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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