Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000002351CARD domain-containing protein. (115 aa)    
Predicted Functional Partners:
ENSACLP00000014482
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.846
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.846
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.757
LOC113031667
PYD and CARD domain containing.
   
 0.699
ENSACLP00000035615
Uncharacterized protein.
   
 0.621
ENSACLP00000035628
Interleukin-1.
   
 0.621
ENSACLP00000018312
Baculoviral IAP repeat containing 6.
   
 0.587
ENSACLP00000007825
CARD domain-containing protein.
  
  
 
0.555
ENSACLP00000025778
CARD domain-containing protein.
  
  
 
0.554
ENSACLP00000025183
CARD domain-containing protein.
  
  
 
0.553
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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