| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LIAS | LOC113022645 | ENSACLP00000022826 | ENSACLP00000002363 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.962 |
| LIAS | dld | ENSACLP00000022826 | ENSACLP00000001913 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Dihydrolipoyl dehydrogenase. | 0.662 |
| LIAS | gldc | ENSACLP00000022826 | ENSACLP00000029148 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.589 |
| LIAS | lipt1 | ENSACLP00000022826 | ENSACLP00000008112 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Lipoyltransferase 1. | 0.975 |
| LIAS | lipt2 | ENSACLP00000022826 | ENSACLP00000015010 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. | 0.972 |
| LOC113022645 | LIAS | ENSACLP00000002363 | ENSACLP00000022826 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.962 |
| LOC113022645 | SHMT2 | ENSACLP00000002363 | ENSACLP00000032070 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.949 |
| LOC113022645 | amt | ENSACLP00000002363 | ENSACLP00000028936 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.998 |
| LOC113022645 | dld | ENSACLP00000002363 | ENSACLP00000001913 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Dihydrolipoyl dehydrogenase. | 0.981 |
| LOC113022645 | dmgdh | ENSACLP00000002363 | ENSACLP00000039067 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Dimethylglycine dehydrogenase. | 0.959 |
| LOC113022645 | gldc | ENSACLP00000002363 | ENSACLP00000029148 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.998 |
| LOC113022645 | lipt1 | ENSACLP00000002363 | ENSACLP00000008112 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Lipoyltransferase 1. | 0.949 |
| LOC113022645 | lipt2 | ENSACLP00000002363 | ENSACLP00000015010 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. | 0.961 |
| LOC113022645 | pdpr | ENSACLP00000002363 | ENSACLP00000029447 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Pyruvate dehydrogenase phosphatase regulatory subunit. | 0.959 |
| LOC113022645 | sardh | ENSACLP00000002363 | ENSACLP00000032933 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Sarcosine dehydrogenase. | 0.959 |
| SHMT2 | LOC113022645 | ENSACLP00000032070 | ENSACLP00000002363 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.949 |
| SHMT2 | amt | ENSACLP00000032070 | ENSACLP00000028936 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.970 |
| SHMT2 | dld | ENSACLP00000032070 | ENSACLP00000001913 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Dihydrolipoyl dehydrogenase. | 0.921 |
| SHMT2 | dmgdh | ENSACLP00000032070 | ENSACLP00000039067 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Dimethylglycine dehydrogenase. | 0.969 |
| SHMT2 | gldc | ENSACLP00000032070 | ENSACLP00000029148 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.977 |