Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACLP00000002368Peptidase S1 domain-containing protein. (239 aa)    
Predicted Functional Partners:
ace2
Angiotensin-converting enzyme.
    
 0.647
LOC113013415
Suppression of tumorigenicity 14b.
     
  0.614
ENSACLP00000017816
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
     
  0.614
ENSACLP00000018009
Uncharacterized protein.
     
  0.614
st14
Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix.
     
  0.614
nme9
NME/NM23 family member 8; Belongs to the NDK family.
   
 0.576
LOC113036663
Transmembrane serine protease 4a; Belongs to the peptidase S1 family.
    
 0.574
plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.569
cltrn
Si:dkey-194e6.1.
    
 0.568
F2RL3
F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
  0.567
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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