Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113030276Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1025 aa)    
Predicted Functional Partners:
ENSACLP00000030532
Kit ligand a.
    
 0.927
LOC113016116
SHC (Src homology 2 domain containing) transforming protein 2.
    
 0.904
LOC113033441
Uncharacterized protein.
    
 0.904
SHC3
SHC adaptor protein 3.
    
 0.904
LOC113010606
Phosphoinositide-3-kinase, regulatory subunit 3a (gamma).
    
 0.904
ENSACLP00000034020
Uncharacterized protein.
    
 0.904
SHC4
SHC adaptor protein 4.
    
 0.903
grb2
Growth factor receptor-bound protein 2b.
    
 0.903
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.903
plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.902
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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