Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113031339Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)    
Predicted Functional Partners:
LOC113032461
Zgc:86598; Belongs to the protein kinase superfamily.
   
 0.988
LOC113008537
Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.
   
 0.988
csnk2a2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.988
LOC113023052
Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily.
   
 0.988
pcgf5
Polycomb group ring finger 5a.
    
 0.954
PCGF3
Polycomb group ring finger 3.
    
 0.952
ENSACLP00000020446
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
  0.938
LOC113006948
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.
    
  0.936
nfkbia
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.
    
  0.936
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit.
    
  0.930
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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