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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALX3ALX homeobox 3. (367 aa)    
Predicted Functional Partners:
LHX3
LIM homeobox 3.
   
0.854
lhx4
LIM homeobox 4.
   
0.854
LOC113034698
LIM domain binding 1a.
    
 0.756
ldb2
LIM domain binding 2a.
    
 0.756
LOC113023769
LIM-domain binding 1b.
    
 0.756
LOC113023510
MADS-box domain-containing protein.
    
 0.596
SRF
Serum response factor.
    
 0.596
ptf1a
Pancreas associated transcription factor 1a.
   
 0.519
tpk1
Thiamin pyrophosphokinase 1.
    
  0.503
ENSACLP00000001517
Achaete-scute family bHLH transcription factor 1b.
   
 0.499
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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