Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
p2rx4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (420 aa)    
Predicted Functional Partners:
chek2
Checkpoint kinase 2.
   
 0.938
ENSACLP00000030513
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
   
 0.930
p2rx5
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.891
ENSACLP00000035782
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.891
p2rx2
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.887
p2rx1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.887
LOC113024806
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.882
p2rx7
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
     
 0.881
ENSACLP00000012724
Glutamate receptor, ionotropic, N-methyl D-aspartate 1b.
   
 
 0.880
grin1
Glutamate receptor, ionotropic, N-methyl D-aspartate 1a.
   
 
 0.880
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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