Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACLP00000002474Adaptor related protein complex 3 subunit delta 1. (1222 aa)    
Predicted Functional Partners:
ap3m2
AP-3 complex subunit mu-2.
   
 0.998
AP3B2
AP-3 complex subunit beta.
   
 0.994
AP3B1
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 0.994
ENSACLP00000009025
Adaptin_N domain-containing protein.
   
 0.992
AP3S1
Adaptor related protein complex 3 subunit sigma 1.
    
 0.989
AP3S2
Adaptor related protein complex 3 subunit sigma 2.
    
 0.989
arpin
Actin related protein 2/3 complex inhibitor.
    
 0.982
vps41
Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.
   
 
 0.935
gak
Cyclin G associated kinase.
   
 0.934
ENSACLP00000009309
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
   
 0.915
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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