Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tbx5Uncharacterized protein. (529 aa)    
Predicted Functional Partners:
nkx2-5
NK2 homeobox 5.
   
 0.951
yap1
Yes-associated protein 1.
    
 0.750
ENSACLP00000002063
Uncharacterized protein.
    
 0.690
hand2
Heart and neural crest derivatives expressed 2.
    
 0.688
LOC113021323
Homeobox B4a.
    
 
 0.654
hoxc9
Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.
    
 
 0.639
hoxb9
Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.
    
 
 0.636
kat2a
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
     
 0.616
LOC113014255
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
     
 0.616
LOC113028753
Fibroblast growth factor binding protein 1b.
      
 0.612
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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