ENSACLP00000002595 protein (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ENSACLP00000002595

Regulatory factor X, 1a (influences HLA class II expression). (875 aa)

Predicted Functional Partners:

LOC113015285

0.912

chek2

0.904

rfxap

0.844

ENSACLP00000008384

0.794

btaf1

0.772

rfxank

0.744

LOC113027848

0.738

LOC113019972

0.738

ENSACLP00000013528

0.723

smarca5

0.719

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000002595	ENSACLP00000008384	ENSACLP00000002595	ENSACLP00000008384	Regulatory factor X, 1a (influences HLA class II expression).	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.794
ENSACLP00000002595	ENSACLP00000013528	ENSACLP00000002595	ENSACLP00000013528	Regulatory factor X, 1a (influences HLA class II expression).	Cyclin D binding myb-like transcription factor 1.	0.723
ENSACLP00000002595	LOC113015285	ENSACLP00000002595	ENSACLP00000007271	Regulatory factor X, 1a (influences HLA class II expression).	Four and a half LIM domains 3b.	0.912
ENSACLP00000002595	LOC113019972	ENSACLP00000002595	ENSACLP00000025827	Regulatory factor X, 1a (influences HLA class II expression).	Forkhead box J1a.	0.738
ENSACLP00000002595	LOC113027848	ENSACLP00000002595	ENSACLP00000025085	Regulatory factor X, 1a (influences HLA class II expression).	Forkhead box J1b.	0.738
ENSACLP00000002595	btaf1	ENSACLP00000002595	ENSACLP00000027218	Regulatory factor X, 1a (influences HLA class II expression).	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.	0.772
ENSACLP00000002595	chek2	ENSACLP00000002595	ENSACLP00000013461	Regulatory factor X, 1a (influences HLA class II expression).	Checkpoint kinase 2.	0.904
ENSACLP00000002595	rfxank	ENSACLP00000002595	ENSACLP00000007107	Regulatory factor X, 1a (influences HLA class II expression).	Regulatory factor X-associated ankyrin-containing protein.	0.744
ENSACLP00000002595	rfxap	ENSACLP00000002595	ENSACLP00000004631	Regulatory factor X, 1a (influences HLA class II expression).	Regulatory factor X-associated protein.	0.844
ENSACLP00000002595	smarca5	ENSACLP00000002595	ENSACLP00000037504	Regulatory factor X, 1a (influences HLA class II expression).	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.	0.719
ENSACLP00000008384	ENSACLP00000002595	ENSACLP00000008384	ENSACLP00000002595	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Regulatory factor X, 1a (influences HLA class II expression).	0.794
ENSACLP00000008384	chek2	ENSACLP00000008384	ENSACLP00000013461	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Checkpoint kinase 2.	0.997
ENSACLP00000008384	smarca5	ENSACLP00000008384	ENSACLP00000037504	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.	0.445
ENSACLP00000013528	ENSACLP00000002595	ENSACLP00000013528	ENSACLP00000002595	Cyclin D binding myb-like transcription factor 1.	Regulatory factor X, 1a (influences HLA class II expression).	0.723
ENSACLP00000013528	btaf1	ENSACLP00000013528	ENSACLP00000027218	Cyclin D binding myb-like transcription factor 1.	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.	0.854
LOC113015285	ENSACLP00000002595	ENSACLP00000007271	ENSACLP00000002595	Four and a half LIM domains 3b.	Regulatory factor X, 1a (influences HLA class II expression).	0.912
LOC113019972	ENSACLP00000002595	ENSACLP00000025827	ENSACLP00000002595	Forkhead box J1a.	Regulatory factor X, 1a (influences HLA class II expression).	0.738
LOC113027848	ENSACLP00000002595	ENSACLP00000025085	ENSACLP00000002595	Forkhead box J1b.	Regulatory factor X, 1a (influences HLA class II expression).	0.738
btaf1	ENSACLP00000002595	ENSACLP00000027218	ENSACLP00000002595	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.	Regulatory factor X, 1a (influences HLA class II expression).	0.772
btaf1	ENSACLP00000013528	ENSACLP00000027218	ENSACLP00000013528	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.	Cyclin D binding myb-like transcription factor 1.	0.854