Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113031207RAB38b, member of RAS oncogene family. (218 aa)    
Predicted Functional Partners:
rabggta
Rab geranylgeranyltransferase subunit alpha.
    
 0.749
gak
Cyclin G associated kinase.
    
 
 0.749
ankrd27
Ankyrin repeat domain 27 (VPS9 domain).
    
 
 0.683
LOC113029983
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.665
ENSACLP00000003376
Uncharacterized protein.
    
 0.665
hps4
HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.
    
 0.634
vti1a
Vesicle transport through interaction with t-SNAREs 1A.
      
 0.603
lta4h
Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.
      
 0.600
ptar1
Protein prenyltransferase alpha subunit repeat containing 1.
    
 0.559
ENSACLP00000014594
HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.
    
 0.536
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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