Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
adat3Adenosine deaminase tRNA specific 3. (340 aa)    
Predicted Functional Partners:
ENSACLP00000009011
CMP/dCMP-type deaminase domain-containing protein.
   
 0.996
smug1
Single-strand-selective monofunctional uracil-DNA glycosylase 1.
   
 0.952
ENSACLP00000008618
Adenosine deaminase tRNA specific 1.
      
 0.861
ctu1
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
  
 
 0.853
tyms
Thymidylate synthetase.
  
 
 0.826
ENSACLP00000008878
Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae).
   
 0.805
tk1
Thymidine kinase.
    
 0.766
adar
Adenosine deaminase RNA specific.
      
 0.708
ENSACLP00000005796
Xanthine dehydrogenase.
    
 0.702
aox1
Aldehyde oxidase 6.
    
 0.702
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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