STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sos2Son of sevenless homolog 2 (Drosophila). (1331 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.993
SHC3
SHC adaptor protein 3.
    
 0.969
SHC4
SHC adaptor protein 4.
    
 0.969
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.969
ENSACLP00000019486
Protein tyrosine phosphatase non-receptor type 11b.
    
 0.967
ptpn6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.967
ptpn11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.967
hras
HRas proto-oncogene, GTPase a.
    
 0.964
LOC113010022
Receptor protein-tyrosine kinase.
    
 0.961
LOC113029559
Receptor protein-tyrosine kinase.
    
 0.961
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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