Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
map3k4Mitogen-activated protein kinase kinase kinase 4. (1581 aa)    
Predicted Functional Partners:
LOC113006604
Growth arrest and DNA damage inducible beta.
    
 0.993
LOC113037131
Ribosomal_L7Ae domain-containing protein.
    
 0.993
gadd45g
Growth arrest and DNA-damage-inducible, gamma a.
    
 0.992
GADD45A
Growth arrest and DNA-damage-inducible, alpha, b.
    
 0.992
LOC113028005
Mitogen-activated protein kinase kinase 6.
    
 0.981
MAP2K6
Mitogen-activated protein kinase kinase 6.
    
 0.981
LOC113027366
Ribosomal_L7Ae domain-containing protein.
    
 0.962
LOC113027367
Growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1.
    
 0.962
LOC113011047
Mitogen-activated protein kinase kinase 2b.
    
 0.953
ENSACLP00000022835
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
    
 0.953
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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