Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
l2hgdhL-2-hydroxyglutarate dehydrogenase. (443 aa)    
Predicted Functional Partners:
LOC113030206
Malate synthase-like.
    
 0.959
cs
Citrate synthase; Belongs to the citrate synthase family.
    
 0.926
aldh4a1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.908
aldh5a1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.906
LOC113028243
Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.905
glud1
Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.905
LOC113026010
Glutamine synthetase.
  
 
 0.885
LOC113010975
Glutamine synthetase.
  
 
 0.884
LOC113016678
Glutamine synthetase.
  
 
 0.884
ENSACLP00000007650
Uncharacterized protein.
     
 0.878
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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