Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC113014962Upstream transcription factor 2, c-fos interacting. (327 aa)    
Predicted Functional Partners:
ENSACLP00000026754
Upstream transcription factor 1.
   
 0.992
sp1
Sp1 transcription factor.
    
 0.770
ENSACLP00000036881
CREB binding protein a.
    
 0.738
LOC113020749
CREB binding protein b.
    
 0.738
ENSACLP00000022669
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor.
    
 
 0.717
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
  0.699
LOC113021131
E1A binding protein p300 b.
    
 0.657
LOC113027597
E1A binding protein p300 a.
    
 0.657
mrps35
Mitochondrial ribosomal protein S35.
    
  0.643
iglon5
IgLON family member 5.
      
 0.608
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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