Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
jak1Tyrosine-protein kinase. (1183 aa)    
Predicted Functional Partners:
ENSACLP00000004595
Signal transducer and activator of transcription.
   
 0.981
socs1
Suppressor of cytokine signaling 1a.
    
 0.981
LOC113022559
Signal transducer and activator of transcription.
   
 0.981
stat1
Signal transducer and activator of transcription.
   
 0.980
LOC113013067
Signal transducer and activator of transcription.
   
 0.978
LOC113020692
Suppressor of cytokine signaling 3a.
    
 0.972
stat4
Signal transducer and activator of transcription.
   
 0.963
LOC113028230
Suppressor of cytokine signaling 3.
    
 0.963
LOC113021295
Erythropoietin receptor.
    
 0.962
socs5
Suppressor of cytokine signaling 5b.
    
 0.962
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.