Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000002812Cyclin-dependent kinase-like 1 (CDC2-related kinase); Belongs to the protein kinase superfamily. (326 aa)    
Predicted Functional Partners:
tmem218
Transmembrane protein 218.
      
 0.658
ENSACLP00000015206
PDZ domain-containing protein.
      
 0.606
sirt1
Deacetylase sirtuin-type domain-containing protein.
    
 
 0.541
LOC113031633
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.537
ENSACLP00000014029
HECT domain-containing protein.
      
 0.471
nphp1
Nephronophthisis 1.
    
 
 0.442
drc1
Uncharacterized protein.
   
  
 0.441
tmem231
Transmembrane protein 231.
      
 0.419
ENSACLP00000006599
MCL1 apoptosis regulator, BCL2 family member b.
      
 0.413
LOC113016700
BCL2 family apoptosis regulator BOK a.
      
 0.413
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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