Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
ENSACLP00000002832TPR_REGION domain-containing protein. (356 aa)    
Predicted Functional Partners:
cops3
COP9 signalosome subunit 3.
    
  0.878
cops2
COP9 signalosome subunit 2.
    
  0.871
eloc
Elongin C paralog a; Belongs to the SKP1 family.
   
 0.861
cul2
Cullin 2; Belongs to the cullin family.
   
 
 0.858
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.829
mrpl28
Mitochondrial ribosomal protein L28.
    
   0.787
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.785
LOC113007350
Amyloid beta (A4) precursor protein b.
    
 0.742
APP
Amyloid beta precursor protein.
    
 0.742
pyroxd2
Pyridine nucleotide-disulphide oxidoreductase domain 2.
   
   0.723
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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