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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyrp1Tyrosinase related protein 1. (521 aa)    
Predicted Functional Partners:
dct
Dopachrome tautomerase.
  
  
 
0.850
ENSACLP00000017239
Tyrosinase-related protein 1b.
  
  
 
0.848
slc24a5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
  
 0.622
mitf
Melanocyte inducing transcription factor a.
   
 
 0.613
LOC113022754
Tankyrase_bdg_C domain-containing protein.
   
  0.612
ripk4
Receptor-interacting serine-threonine kinase 4.
   
  0.591
ENSACLP00000008845
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.587
met
MET proto-oncogene, receptor tyrosine kinase.
    
  0.586
LOC113022284
Macrophage stimulating 1 receptor a.
    
  0.586
mst1r
Macrophage stimulating 1 receptor b.
    
  0.586
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.