tyrp1 protein (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

tyrp1

Tyrosinase related protein 1. (521 aa)

Predicted Functional Partners:

ENSACLP00000008845

0.908

slc24a5

0.897

dct

0.872

ENSACLP00000017239

0.872

ENSACLP00000035771

0.856

ENSACLP00000035858

0.833

mitf

0.828

txnl4b

0.825

sox10

0.796

pax3

0.750

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000008845	ENSACLP00000017239	ENSACLP00000008845	ENSACLP00000017239	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Tyrosinase-related protein 1b.	0.727
ENSACLP00000008845	ENSACLP00000035771	ENSACLP00000008845	ENSACLP00000035771	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Oculocutaneous albinism II.	0.813
ENSACLP00000008845	dct	ENSACLP00000008845	ENSACLP00000010846	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Dopachrome tautomerase.	0.682
ENSACLP00000008845	mitf	ENSACLP00000008845	ENSACLP00000033077	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Melanocyte inducing transcription factor a.	0.751
ENSACLP00000008845	pax3	ENSACLP00000008845	ENSACLP00000020447	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Paired box 3b.	0.522
ENSACLP00000008845	slc24a5	ENSACLP00000008845	ENSACLP00000026132	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.719
ENSACLP00000008845	sox10	ENSACLP00000008845	ENSACLP00000023780	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	SRY-box transcription factor 10.	0.420
ENSACLP00000008845	tyrp1	ENSACLP00000008845	ENSACLP00000002892	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Tyrosinase related protein 1.	0.908
ENSACLP00000017239	ENSACLP00000008845	ENSACLP00000017239	ENSACLP00000008845	Tyrosinase-related protein 1b.	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	0.727
ENSACLP00000017239	ENSACLP00000035771	ENSACLP00000017239	ENSACLP00000035771	Tyrosinase-related protein 1b.	Oculocutaneous albinism II.	0.707
ENSACLP00000017239	ENSACLP00000035858	ENSACLP00000017239	ENSACLP00000035858	Tyrosinase-related protein 1b.	Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family.	0.653
ENSACLP00000017239	dct	ENSACLP00000017239	ENSACLP00000010846	Tyrosinase-related protein 1b.	Dopachrome tautomerase.	0.872
ENSACLP00000017239	mitf	ENSACLP00000017239	ENSACLP00000033077	Tyrosinase-related protein 1b.	Melanocyte inducing transcription factor a.	0.733
ENSACLP00000017239	pax3	ENSACLP00000017239	ENSACLP00000020447	Tyrosinase-related protein 1b.	Paired box 3b.	0.561
ENSACLP00000017239	slc24a5	ENSACLP00000017239	ENSACLP00000026132	Tyrosinase-related protein 1b.	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.693
ENSACLP00000017239	sox10	ENSACLP00000017239	ENSACLP00000023780	Tyrosinase-related protein 1b.	SRY-box transcription factor 10.	0.684
ENSACLP00000017239	txnl4b	ENSACLP00000017239	ENSACLP00000035855	Tyrosinase-related protein 1b.	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.	0.635
ENSACLP00000017239	tyrp1	ENSACLP00000017239	ENSACLP00000002892	Tyrosinase-related protein 1b.	Tyrosinase related protein 1.	0.872
ENSACLP00000035771	ENSACLP00000008845	ENSACLP00000035771	ENSACLP00000008845	Oculocutaneous albinism II.	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	0.813
ENSACLP00000035771	ENSACLP00000017239	ENSACLP00000035771	ENSACLP00000017239	Oculocutaneous albinism II.	Tyrosinase-related protein 1b.	0.707