Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cdk12Cyclin-dependent kinase 12. (1351 aa)    
Predicted Functional Partners:
ccnk
Cyclin K; Belongs to the cyclin family.
   
 0.986
ENSACLP00000016700
Transcription elongation factor SPT5.
    
 0.968
cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.
    
 0.954
cdk7
Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.
    
0.942
polr2a
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.935
ENSACLP00000035168
Uncharacterized protein.
   
 0.935
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.911
ccnt2
Cyclin T2; Belongs to the cyclin family.
   
 0.901
LOC113013617
Cyclin T1; Belongs to the cyclin family.
   
 0.901
ENSACLP00000040608
Cyclin N-terminal domain-containing protein.
   
 0.901
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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