Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
LOC113028261GTP cyclohydrolase 2. (221 aa)    
Predicted Functional Partners:
ENSACLP00000004314
GTP cyclohydrolase I feedback regulator.
    
 0.985
pts
6-pyruvoyltetrahydropterin synthase.
  
 
 0.959
mocs1
Molybdenum cofactor synthesis 1.
    
 0.913
ENSACLP00000011377
NME/NM23 nucleoside diphosphate kinase 3; Belongs to the NDK family.
   
  0.894
GUCY2C
Guanylate cyclase.
     
 0.894
LOC113020127
NDK domain-containing protein; Belongs to the NDK family.
   
  0.894
LOC113027606
Guanylate cyclase.
     
 0.894
ENSACLP00000010376
Nucleoside diphosphate kinase.
   
  0.893
nme6
Nucleoside diphosphate kinase.
   
  0.892
nme7
Nucleoside diphosphate kinase 7; Belongs to the NDK family.
   
  0.892
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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