Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACLP00000002963Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (531 aa)    
Predicted Functional Partners:
LOC113016248
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
    
 0.894
LOC113015699
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.890
LOC113011723
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.890
LOC113033130
Uncharacterized protein.
    
 0.890
GNA14
G protein subunit alpha 14.
    
 0.890
ENSACLP00000029412
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.890
LOC113025585
Guanine nucleotide binding protein (G protein), alpha 14.
    
 0.884
LOC113025584
Uncharacterized protein.
    
 0.884
ENSACLP00000002811
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.884
LOC113012055
Bradykinin receptor B1.
     
 0.873
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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