Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000002986RING-type domain-containing protein. (206 aa)    
Predicted Functional Partners:
ENSACLP00000031548
Notch receptor 1b.
    
 0.881
LOC113025559
Notch receptor 1a.
    
 0.881
LOC113020561
Notch receptor 3.
    
  0.880
LOC113016878
Notch receptor 2.
    
  0.880
ENSACLP00000003772
Uncharacterized protein.
    
  0.861
rnf166
Ring finger protein 166.
    
 
 0.860
dtx3
Zgc:66440.
     
  0.854
chfr
Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase.
    
 
 0.847
LOC113018689
Deltex 4, E3 ubiquitin ligase a.
     
  0.801
ENSACLP00000011428
WWE domain-containing protein.
     
  0.801
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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