Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACLP00000002992Calcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (458 aa)    
Predicted Functional Partners:
calm1
Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family.
    
 0.926
calm1-2
Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family.
    
 0.926
calm1-3
Calmodulin.
    
 0.926
ENSACLP00000037109
Uncharacterized protein; Belongs to the calmodulin family.
    
 0.926
CALML6
Calmodulin like 6.
    
 0.922
ENSACLP00000020804
Calmodulin-like 4a.
    
 0.903
ENSACLP00000034132
Calmodulin-like 4b.
    
 0.900
FBXO43
F-box protein 43.
    
 0.899
cdc25b
Rhodanese domain-containing protein.
     
 0.892
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.882
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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