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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)    
Predicted Functional Partners:
ENSACLP00000013202
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.919
fgfr2
Fibroblast growth factor receptor.
    
 0.915
pdgfra
Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.913
ENSACLP00000039055
Uncharacterized protein.
    
 0.913
tie1
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1.
    
 0.904
fgfr3
Fibroblast growth factor receptor.
    
 0.903
ENSACLP00000023118
Fibroblast growth factor receptor 4; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.903
LOC113033119
Fibroblast growth factor receptor.
    
 0.903
ENSACLP00000029128
Uncharacterized protein.
    
 0.903
ENSACLP00000029170
Uncharacterized protein.
    
 0.902
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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