tmem86a protein (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

tmem86a

Transmembrane protein 86A. (237 aa)

Predicted Functional Partners:

ENSACLP00000010045

0.798

ENSACLP00000037343

0.798

c10h11orf54

0.534

get3

0.534

LOC113030206

0.520

hspa9

0.491

mmp14

0.491

gdf15

0.487

mmp15

0.480

LOC113031966

0.478

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000010045	ENSACLP00000037343	ENSACLP00000010045	ENSACLP00000037343	Si:dkey-177p2.18.	Uncharacterized protein.	0.858
ENSACLP00000010045	LOC113031966	ENSACLP00000010045	ENSACLP00000000340	Si:dkey-177p2.18.	Heat shock cognate 70; Belongs to the heat shock protein 70 family.	0.465
ENSACLP00000010045	tmem86a	ENSACLP00000010045	ENSACLP00000003102	Si:dkey-177p2.18.	Transmembrane protein 86A.	0.798
ENSACLP00000037343	ENSACLP00000010045	ENSACLP00000037343	ENSACLP00000010045	Uncharacterized protein.	Si:dkey-177p2.18.	0.858
ENSACLP00000037343	LOC113031966	ENSACLP00000037343	ENSACLP00000000340	Uncharacterized protein.	Heat shock cognate 70; Belongs to the heat shock protein 70 family.	0.465
ENSACLP00000037343	tmem86a	ENSACLP00000037343	ENSACLP00000003102	Uncharacterized protein.	Transmembrane protein 86A.	0.798
LOC113030206	tmem86a	ENSACLP00000009612	ENSACLP00000003102	Malate synthase-like.	Transmembrane protein 86A.	0.520
LOC113031966	ENSACLP00000010045	ENSACLP00000000340	ENSACLP00000010045	Heat shock cognate 70; Belongs to the heat shock protein 70 family.	Si:dkey-177p2.18.	0.465
LOC113031966	ENSACLP00000037343	ENSACLP00000000340	ENSACLP00000037343	Heat shock cognate 70; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.465
LOC113031966	hspa9	ENSACLP00000000340	ENSACLP00000027267	Heat shock cognate 70; Belongs to the heat shock protein 70 family.	Heat shock protein 9; Belongs to the heat shock protein 70 family.	0.759
LOC113031966	tmem86a	ENSACLP00000000340	ENSACLP00000003102	Heat shock cognate 70; Belongs to the heat shock protein 70 family.	Transmembrane protein 86A.	0.478
c10h11orf54	tmem86a	ENSACLP00000014874	ENSACLP00000003102	Zgc:85789.	Transmembrane protein 86A.	0.534
gdf15	get3	ENSACLP00000011673	ENSACLP00000022033	TGF_BETA_2 domain-containing protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.432
gdf15	tmem86a	ENSACLP00000011673	ENSACLP00000003102	TGF_BETA_2 domain-containing protein.	Transmembrane protein 86A.	0.487
get3	gdf15	ENSACLP00000022033	ENSACLP00000011673	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	TGF_BETA_2 domain-containing protein.	0.432
get3	tmem86a	ENSACLP00000022033	ENSACLP00000003102	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Transmembrane protein 86A.	0.534
hspa9	LOC113031966	ENSACLP00000027267	ENSACLP00000000340	Heat shock protein 9; Belongs to the heat shock protein 70 family.	Heat shock cognate 70; Belongs to the heat shock protein 70 family.	0.759
hspa9	tmem86a	ENSACLP00000027267	ENSACLP00000003102	Heat shock protein 9; Belongs to the heat shock protein 70 family.	Transmembrane protein 86A.	0.491
mmp14	tmem86a	ENSACLP00000029353	ENSACLP00000003102	Matrix metallopeptidase 14b (membrane-inserted).	Transmembrane protein 86A.	0.491
mmp15	tmem86a	ENSACLP00000032952	ENSACLP00000003102	Matrix metallopeptidase 15b.	Transmembrane protein 86A.	0.480