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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC113032455Retinoid x receptor, beta b. (444 aa)    
Predicted Functional Partners:
nr1h3
Nuclear receptor subfamily 1, group H, member 3.
   
0.976
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.949
PPARG
Peroxisome proliferator activated receptor gamma.
    
0.938
ppard
Peroxisome proliferator-activated receptor delta b.
    
0.919
LOC113013152
Nuclear receptor subfamily 1, group H, member 5.
   
0.909
nr1h4
Nuclear receptor subfamily 1, group H, member 4.
   
0.909
ENSACLP00000010348
Nuclear receptor corepressor 1.
    
 0.902
ncor2
Nuclear receptor corepressor 2.
    
 0.902
LOC113009960
Uncharacterized protein.
   
 0.871
ncoa1
Nuclear receptor coactivator 1.
   
 0.871
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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