tbc1d23 protein (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

tbc1d23

TBC1 domain family, member 23. (696 aa)

Predicted Functional Partners:

ENSACLP00000015526

0.973

osgep

0.973

fam91a1

0.967

ENSACLP00000034241

0.932

ENSACLP00000001532

0.810

tbc1d5

0.667

cdc16

0.657

spryd7

0.655

ENSACLP00000032545

0.655

osgepl1

0.632

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000001532	fam91a1	ENSACLP00000001532	ENSACLP00000026188	Zgc:153240.	Family with sequence similarity 91 member A1.	0.995
ENSACLP00000001532	tbc1d23	ENSACLP00000001532	ENSACLP00000003124	Zgc:153240.	TBC1 domain family, member 23.	0.810
ENSACLP00000015526	ENSACLP00000034241	ENSACLP00000015526	ENSACLP00000034241	Glutaredoxin 3.	Apoptosis inhibitor 5.	0.749
ENSACLP00000015526	osgep	ENSACLP00000015526	ENSACLP00000027051	Glutaredoxin 3.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.798
ENSACLP00000015526	tbc1d23	ENSACLP00000015526	ENSACLP00000003124	Glutaredoxin 3.	TBC1 domain family, member 23.	0.973
ENSACLP00000032545	spryd7	ENSACLP00000032545	ENSACLP00000000753	Adaptor related protein complex 1 associated regulatory protein.	SPRY domain containing 7b.	0.657
ENSACLP00000032545	tbc1d23	ENSACLP00000032545	ENSACLP00000003124	Adaptor related protein complex 1 associated regulatory protein.	TBC1 domain family, member 23.	0.655
ENSACLP00000034241	ENSACLP00000015526	ENSACLP00000034241	ENSACLP00000015526	Apoptosis inhibitor 5.	Glutaredoxin 3.	0.749
ENSACLP00000034241	osgep	ENSACLP00000034241	ENSACLP00000027051	Apoptosis inhibitor 5.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.749
ENSACLP00000034241	tbc1d23	ENSACLP00000034241	ENSACLP00000003124	Apoptosis inhibitor 5.	TBC1 domain family, member 23.	0.932
cdc16	tbc1d23	ENSACLP00000039031	ENSACLP00000003124	Cell division cycle 16 homolog (S. cerevisiae).	TBC1 domain family, member 23.	0.657
cdc16	tbc1d5	ENSACLP00000039031	ENSACLP00000000576	Cell division cycle 16 homolog (S. cerevisiae).	TBC1 domain family, member 5.	0.508
fam91a1	ENSACLP00000001532	ENSACLP00000026188	ENSACLP00000001532	Family with sequence similarity 91 member A1.	Zgc:153240.	0.995
fam91a1	tbc1d23	ENSACLP00000026188	ENSACLP00000003124	Family with sequence similarity 91 member A1.	TBC1 domain family, member 23.	0.967
osgep	ENSACLP00000015526	ENSACLP00000027051	ENSACLP00000015526	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Glutaredoxin 3.	0.798
osgep	ENSACLP00000034241	ENSACLP00000027051	ENSACLP00000034241	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Apoptosis inhibitor 5.	0.749
osgep	osgepl1	ENSACLP00000027051	ENSACLP00000002697	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.	0.859
osgep	tbc1d23	ENSACLP00000027051	ENSACLP00000003124	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	TBC1 domain family, member 23.	0.973
osgepl1	osgep	ENSACLP00000002697	ENSACLP00000027051	Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.859
osgepl1	tbc1d23	ENSACLP00000002697	ENSACLP00000003124	Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.	TBC1 domain family, member 23.	0.632