Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003132RAB8A, member RAS oncogene family. (154 aa)    
Predicted Functional Partners:
ENSACLP00000032760
Zgc:100846.
    
 0.905
wdr41
WD repeat domain 41.
     
 0.905
MICALL1
MICAL like 1.
    
 0.896
LOC113024464
Smith-Magenis syndrome chromosome region, candidate 8b.
    
 0.886
LOC113021135
Smith-Magenis syndrome chromosome region, candidate 8a.
    
 0.886
sqstm1
Sequestosome 1.
    
 0.876
micall2
Mical-like 2a.
    
 0.862
ENSACLP00000008450
Mical-like 2b.
    
 0.862
ENSACLP00000035250
Rab interacting lysosomal protein-like 2.
   
 
 0.844
LOC113033143
Uncharacterized protein.
   
 0.843
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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