Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
faf2Fas associated factor family member 2. (445 aa)    
Predicted Functional Partners:
ubxn1
UBX domain protein 1.
    
 0.996
ufd1
Ubiquitin recognition factor in ER associated degradation 1.
    
 
 0.989
ENSACLP00000035637
UBX domain-containing protein 7.
   
 
 0.989
ENSACLP00000026794
UBA domain containing 2.
    
 
 0.987
vcp
Valosin containing protein; Belongs to the AAA ATPase family.
    
 0.986
ENSACLP00000035605
Zgc:136908; Belongs to the AAA ATPase family.
    
 0.986
sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 
 0.985
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 
 0.984
pex19
Peroxisomal biogenesis factor 19.
    
 
 0.973
ubxn6
UBX domain protein 6.
    
 0.964
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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