Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fechFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (403 aa)    
Predicted Functional Partners:
ENSACLP00000007618
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 0.996
ENSACLP00000026032
Frataxin.
    
 0.995
abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7.
   
 
 0.972
urod
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
  
 0.970
LOC113028171
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.
     
 0.948
clpp
ATP-dependent Clp protease proteolytic subunit.
   
 0.943
LOC113030105
Hephaestin-like 1b; Belongs to the multicopper oxidase family.
   
 
 0.940
LOC113009037
Ceruloplasmin; Belongs to the multicopper oxidase family.
   
 
 0.940
pgrmc1
Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.
    
 
 0.934
LOC113023263
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
    
 0.924
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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