STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003215Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (424 aa)    
Predicted Functional Partners:
strada
STE20 related adaptor alpha.
    
 0.992
STRADB
STE20 related adaptor beta.
    
 0.992
LOC113018712
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.991
cab39
Calcium binding protein 39.
    
 0.985
LOC113016174
Calcium binding protein 39-like.
    
 0.984
prkaa2
Non-specific serine/threonine protein kinase.
    
 0.984
LOC113033507
Calcium binding protein 39, like 1.
    
 0.984
LOC113033507-2
Calcium-binding protein 39-like.
    
 0.984
prkaa1
Non-specific serine/threonine protein kinase.
    
 0.984
LOC113034208
Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b.
    
 0.935
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.