Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003216Roundabout, axon guidance receptor, homolog 2 (Drosophila). (1294 aa)    
Predicted Functional Partners:
LOC113030565
Slit homolog 3 (Drosophila).
   
 0.901
abl1
Tyrosine-protein kinase.
   
 0.899
abl2
Tyrosine-protein kinase.
   
 0.899
slit1
Slit homolog 1a (Drosophila).
   
 0.876
LOC113024679
Slit homolog 1b (Drosophila).
   
 0.876
ENSACLP00000024091
Slit homolog 2 (Drosophila).
   
 0.876
ENSACLP00000003461
Roundabout, axon guidance receptor, homolog 3 (Drosophila).
    
 0.834
nck2
Cytoplasmic protein.
    
 0.824
nck1
Cytoplasmic protein.
    
 0.824
nyx
Nyctalopin.
   
 0.823
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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