Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003245C3H1-type domain-containing protein. (545 aa)    
Predicted Functional Partners:
LOC113025905
Ring finger and CCCH-type domains 2.
   
 
 0.903
ENSACLP00000003284
Uncharacterized protein.
 
      0.851
rc3h1
Ring finger and CCCH-type domains 1b.
   
 
 0.783
SMYD3
SET and MYND domain containing 3.
    
 
 0.780
ENSACLP00000021173
CCR4-NOT transcription complex, subunit 1.
   
 
 0.754
LOC113024137
SET and MYND domain containing 2a.
    
 
 0.687
LOC113006810
Uncharacterized protein.
    
 
 0.687
pan3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
   
   0.687
ENSACLP00000011575
Receptor for activated C kinase 1.
    
   0.620
LOC113036056
Receptor for activated C kinase 1.
    
   0.620
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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